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• Huangong Li, Zheng Zhu, Dongqi Wu, Yongyuan Ju, Dan Li, Keke Zou, Chaonan Zhu, Jingyu Zhang, Guoliang Zhu and Lixin Zhang. Taming Highly Enolizable Aldehydes via Enzyme Catalysis for Enantiocomplementary Construction of β-Hydroxyphosphonates. Journal of the American Chemical Society. 2025-01. DOI: 10.1021/jacs.4c11957.
• WenQing Zheng, XinXin Zhu, Zheng Zhu, Tairan Yang, Lifen Zheng, Rui Pan, Shenlin Wang, Lixin Zhang, Qi Chen and JianHe Xu. Access to Axially Chiral Biaryl Benzylamines via Ancestral Enzyme-Enabled Reductive Amination Desymmetrization. ACS Catalysis. 2025-01. DOI: 10.1021/acscatal.4c06881.
• Houming Zhou, Chengyu Zhang, Zilong Li, Menglei Xia, Zhenghong Li, Zhengduo Wang, Gao-Yi Tan, Ying Luo, Lixin Zhang and Weishan Wang. Systematic Development of a Highly Efficient Cell Factory for 5-Aminolevulinic Acid Production. Trends in Biotechnology. 2024-11. DOI: 10.1016/j.tibtech.2024.06.004.
• Weiyan Zhang, Xinye Wang, Guoliang Zhu, Bin Zhu, Kaitong Peng, Tom Hsiang, Lixin Zhang and Xueting Liu. Function Switch of a Fungal Sesterterpene Synthase through Molecular Dynamics Simulation Assisted Alteration of an Aromatic Residue Cluster in the Active Pocket of PfNS. Angewandte Chemie International Edition. 2024-09. DOI: 10.1002/anie.202406246.
• Haihong Chen, Yaohong Wang, Weishan Wang, Ting Cao, Lu Zhang, Zhengduo Wang, Xuran Chi, Tong Shi, Huangwei Wang, Xinwei He, Mindong Liang, Mengxue Yang, Wenyi Jiang, Dongyuan Lv, Jiaming Yu, Guoliang Zhu, Yongtao Xie, Bei Gao, Xinye Wang, Xueting Liu, Youyuan Li, Liming Ouyang, Jingyu Zhang, Huimin Liu, Zilong Li, Yaojun Tong, Xuekui Xia, Gao-Yi Tan and Lixin Zhang. High-yield Porphyrin Production through Metabolic Engineering and Biocatalysis. Nature Biotechnology. 2024-06. DOI: 10.1038/s41587-024-02267-3.
• Shuliu Wang, Xiaoqian Zeng, Yue Jiang, Weishan Wang, Linquan Bai, Yinhua Lu, Lixin Zhang and Gao-Yi Tan. Unleashing the Potential: Type I CRISPR-Cas Systems in Actinomycetes for Genome Editing. Natural Product Reports. 2024-06. DOI: 10.1039/D4NP00010B.
• Xinye Wang, Sha Hu, Jun Wang, Tao Zhang, Ke Ye, Aiwen Wen, Guoliang Zhu, Arturo Vegas, Lixin Zhang and Wupeng Yan. Biochemical and Structural Characterization of OvoA_Th2: A Mononuclear Nonheme Iron Enzyme from Hydrogenimonas thermophila for Ovothiol Biosynthesis. ACS Catalysis. 2023-11. DOI: 10.1021/acscatal.3c04026.
• Zhiheng Yang, Zilong Li, Bixiao Li, Ruihong Bu, Gao-Yi Tan, Zhengduo Wang, Hao Yan, Zhenguo Xin, Guojian Zhang, Ming Li, Hua Xiang, Lixin Zhang and Weishan Wang. A Thermostable Type IB CRISPR-Cas System for Orthogonal and Multiplexed Genetic Engineering. Nature Communications. 2023-10. DOI: 10.1038/s41467-023-41973-5.
• Haishuo Ji, Lei Wan, Yanxin Gao, Ping Du, Wenjin Li, Hang Luo, Jiarui Ning, Yingying Zhao, Huangwei Wang, Lixin Zhang and Liyun Zhang. Hydrogenase as the Basis for Green Hydrogen Production and Utilization. Journal of Energy Chemistry. 2023-10. DOI: 10.1016/j.jechem.2023.06.018.
• Yuting Shuai, Anan Xu, Jiayi Li, Zhaoxi Han, Dini Ma, Hairong Duan, Xinye Wang, Lan Jiang, Jingyu Zhang, Gao-Yi Tan, Xueting Liu, Yi-Lei Zhao, Yaojun Tong, Shenlin Wang, Xinyi He, Zixin Deng, Guang Liu and Lixin Zhang. Profile and Relaxation of Sequence-Specificity of DNA Sulfur Binding Domains Facilitate New Nucleic Acid Detection Platform. Science Bulletin. 2023-08. DOI: 10.1016/j.scib.2023.07.012.
• Donghui Zhang, Chao Shi, Zihao Cong, Qi Chen, Yufang Bi, Junyu Zhang, Kaiqian Ma, Shiqi Liu, Jiawei Gu, Minzhang Chen, Ziyi Lu, Haodong Zhang, Jiayang Xie, Ximian Xiao, Longqiang Liu, Weinan Jiang, Ning Shao, Sheng Chen, Min Zhou, Xiaoyan Shao, Yidong Dai, Maoquan Li, Lixin Zhang and Runhui Liu. Microbial Metabolite Inspired β-Peptide Polymers Displaying Potent and Selective Antifungal Activity. Advanced Science. 2022-03. DOI: 10.1002/advs.202104871.
• Mindong Liang, Leshi Liu, Fei Xu, Xiaoqian Zeng, Ruijun Wang, Jinling Yang, Weishan Wang, Loganathan Karthik, Jiakun Liu, Zhiheng Yang, Guoliang Zhu, Shuliu Wang, Linquan Bai, Yaojun Tong, Xueting Liu, Min Wu, Li-Xin Zhang and Gao-Yi Tan. Activating Cryptic Biosynthetic Gene Cluster through a CRISPR–Cas12a-Mediated Direct Cloning Approach. Nucleic Acids Research. 2022-03. DOI: 10.1093/nar/gkac181.
• Yaojun Tong, Jingyu Zhang, Nuo Sun, Xiang-Ming Wang, Qi Wei, Yu Zhang, Ren Huang, Yingying Pu, Huanqin Dai, Biao Ren, Gang Pei, Fuhang Song, Guoliang Zhu, Xinye Wang, Xuekui Xia, Xiangyin Chen, Lan Jiang, Shenlin Wang, Liming Ouyang, Ning Xie, Buchang Zhang, Yuanying Jiang, Xueting Liu, Richard Calderone, Fan Bai, Lixin Zhang and Gil Alterovitz. Berberine Reverses Multidrug Resistance in Candida Albicans by Hijacking the Drug Efflux Pump Mdr1p. Science Bulletin. 2021-09. DOI: 10.1016/j.scib.2020.12.035.
• Jianying Han, Xueting Liu, Lixin Zhang, Ronald J. Quinn and Yunjiang Feng. Anti-Mycobacterial Natural Products and Mechanisms of Action. Natural product reports. 2021-07. DOI: 10.1039/D1NP00011J.
• Qian Du, Biao Ren, Jinzhi He, Xian Peng, Qiang Guo, Liwei Zheng, Jiyao Li, Huanqin Dai, Vivian Chen, Lixin Zhang, Xuedong Zhou and Xin Xu. Candida Albicans Promotes Tooth Decay by Inducing Oral Microbial Dysbiosis. The ISME journal. 2020-11. DOI: 10.1038/s41396-020-00823-8.
• Xiangxiang Zhao, Shanshan Li, Guang Liu, Zhong Wang, Zhiheng Yang, Quanwei Zhang, Mindong Liang, Jiakun Liu, Zilong Li, Yaojun Tong, Guoliang Zhu, Xinye Wang, Lan Jiang, Weishan Wang, Gao-Yi Tan and Lixin Zhang. A Versatile Biosensing Platform Coupling CRISPR–Cas12a and Aptamers for Detection of Diverse Analytes. Science Bulletin. 2021-01. DOI: 10.1016/j.scib.2020.09.004.
• Fan Wu, Jing Zhang, Fuhang Song, Sanshan Wang, Hui Guo, Qi Wei, Huanqin Dai, Xiangyin Chen, Xuekui Xia, Xueting Liu, Lixin Zhang, Jin-Quan Yu and Xiaoguang Lei. Chrysomycin A Derivatives for the Treatment of Multi-Drug-Resistant Tuberculosis. ACS Central Science. 2020-05. DOI: 10.1021/acscentsci.0c00122.
• Weishan Wang, Shanshan Li, Zilong Li, Jingyu Zhang, Keqiang Fan, Gaoyi Tan, Guomin Ai, Sin Man Lam, Guanghou Shui, Zhiheng Yang, Hongzhong Lu, Pinjiao Jin, Yihong Li, Xiangyin Chen, Xuekui Xia, Xueting Liu, H Kathleen Dannelly, Chen Yang, Yi Yang, Siliang Zhang, Gil Alterovitz, Wensheng Xiang and Lixin Zhang. Harnessing the Intracellular Triacylglycerols for Titer Improvement of Polyketides in Streptomyces. Nature Biotechnology. 2019-12. DOI: 10.1038/s41587-019-0335-4.
• Xianjun Chen, Dasheng Zhang, Ni Su, Bingkun Bao, Xin Xie, Fangting Zuo, Lipeng Yang, Hui Wang, Li Jiang, Qiuning Lin, Mengyue Fang, Ningfeng Li, Xin Hua, Zhengda Chen, Chunyan Bao, Jinjin Xu, Wenli Du, Lixin Zhang, Yuzheng Zhao, Linyong Zhu, Joseph Loscalzo and Yi Yang. Visualizing RNA Dynamics in Live Cells with Bright and Stable Fluorescent RNAs. Nature Biotechnology. 2019-09. DOI: 10.1038/s41587-019-0249-1.
• Mindong Liang, Zilong Li, Weishan Wang, Jiakun Liu, Leshi Liu, Guoliang Zhu, Loganathan Karthik, Man Wang, Ke-Feng Wang, Zhong Wang, Jing Yu, Yuting Shuai, Jiaming Yu, Lu Zhang, Zhiheng Yang, Chuan Li, Qian Zhang, Tong Shi, Liming Zhou, Feng Xie, Huanqin Dai, Xueting Liu, Jingyu Zhang, Guang Liu, Ying Zhuo, Buchang Zhang, Chenli Liu, Shanshan Li, Xuekui Xia, Yaojun Tong, Yanwen Liu, Gil Alterovitz, Gao-Yi Tan and Li-Xin Zhang. A CRISPR-Cas12a-Derived Biosensing Platform for the Highly Sensitive Detection of Diverse Small Molecules. Nature Communications. 2019-08. DOI: 10.1038/s41467-019-11648-1.
• Jiaqian Cao, Yongpeng Yao, Keqiang Fan, Gaoyi Tan, Wensheng Xiang, Xuekui Xia, Shanshan Li, Weishan Wang and Lixin Zhang. Harnessing a Previously Unidentified Capability of Bacterial Allosteric Transcription Factors for Sensing Diverse Small Molecules in Vitro. Science Advances. 2018-11. DOI: 10.1126/sciadv.aau4602.

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